The formation of squaramic acids and squaryl diamides by the reaction of squaric acid with alkyl isocyanides
Posted on 4. July, 2013.
The reaction between squaric acid with one equivalent of alkyl isocyanides such as t-butyl isocyanide, cyclohexyl isocyanide and n-butyl isocyanide in ethanol at room temperature after 3h afforded the corresponding squaramic acid derivatives.
Novel uses of nanoparticle catalytic systems
Posted on 23. May, 2013.
Easily prepared and recoverable nanoparticles with a diameter of 10–40 nm, with a high surface area and stability may provide a catalytic system or the support for a catalyst.
Traditional Chinese medicine - chemistry and application
Posted on 24. April, 2013.
Amongst the many aspects of modern Chinese chemistry described in the Journal of Chemical Research during 2012, are phytochemical investigations into the constituents of traditional Chinese medicines derived from plants and fungi. Such studies have afforded new medicines to treat diseases such as Alzheimer’s, malaria and cancer.
Advances in aromatic chemistry reported in the Journal of Chemical Research in 2012
Posted on 28. March, 2013.
During 2012 a number of useful papers have appeared in the Journal of Chemical Research reporting advances in aromatic chemistry.
First total synthesis of fuscain
Posted on 20. December, 2012.
Fuscain is a new furanolactam isolated from the sponge Phacellis fusca from the South China Sea. Furan analogues isolated from marine organisms have valuable medicinal properties. The first total synthesis of fuscain is reported in Journal of Chemical Research December issue. The key step in the synthesis is the formation of seven-membered lactam by acylation of a furan ring using the mild Lewis acid CuSO4•5H2O.
Efficient Odorant Synthesis
Posted on 20. September, 2012.
2-Nonen-4-olide occurs naturally in the volatile components of various foods and plant extracts, such as stewed beef/vegetable gravy, sunflower oil, Chinese white salted noodles watermelon, potato crisps, lard cured with spices and aromatic herbs, mushrooms, French fries, and flue-cured tobacco. It has an oily, coconut-like, and rancid odour. A simple, efficient and low cost synthesis of this odorant is reported in the August issue of Journal of Chemical Research.
Highlights in natural products published in the Journal of Chemical Research in 2011
Posted on 29. May, 2012.
Various aspects of the isolation, synthesis, chemistry and biological activity of a range of natural products were published in 2011 Journal of Chemical Research. In medicinal chemistry, most of today's antibacterials are chemically semisynthetic modifications of natural compounds emanating from trees, shrubs and fungi.
Highlights of synthetic methods published in the Journal of Chemical Research in 2011
Posted on 29. May, 2012.
During 2011 the Journal of Chemical Research published over 200 papers. Many reported the synthesis and chemistry of specific groups of compounds whilst others have described useful additions to synthetic methodology. Heck and Knoevenagel reactions, nanoparticle as catalysts are just some of the methodologies reviewed.
Micro reactors: industrial results
Posted on 24. April, 2012.
Micro reactors and flow reactors have many advantages as tools in organic synthesis. A review in the April issue of Journal of Chemical Research describes how small reactor volumes enable reactions to be performed on an industrial scale more efficiently and safely than when using batch processes.