Mailing List

For all the latest news and features, sign up to receive our FREE updates by email:

Syntheses and structures of a class of bridged bis(amidinate)s and derivatives

Posted on 20. June, 2018.

Amidinates are versatile ligands used in the fields of coordination and organometallic chemistry because their steric and electronic properties can be easily modulated by varying the substituents on the C and N atoms.

Read more
A convenient synthesis of gimeracil

Posted on 6. March, 2018.

A practical three-step synthetic approach to gimeracil in a 68% overall yield is described, using 2,4-dimethoxypyridine as the starting material with 3,5-dichloro-2,4-dimethoxypyridine and 3,5-dichloro-2,4-dihydroxypyridine as intermediates. The advantages of this procedure include short reaction steps, simple operation and good yield.

Read more
Substitute group-tuned Schiff-base manganese(III)-based cyanide-bridged bimetallic complexes: synthesis, crystal structures and magnetic properties

Posted on 5. March, 2018.

The trinuclear cyanide-bridged heterometallic Pd(ii)–Mn(iii) complexes {[Mn(L1)(H2O)]2[Pd(CN)4]} and {[Mn(L2)(H2O)]2[Pd(CN)4]}·2H2O(L1 = N,N′-1,2-propylene-bis(3-methoxysalicylideneiminate; L2 = N,N′-1,2-propylene-bis(3-ethoxysalicylideneiminate) were obtained and structurally and magnetically characterised. X-ray diffraction revealed their cyanide-bridged trinuclear core nature with a conformational difference. The magnetic susceptibilities of the two complexes revealed overall weak antiferromagnetic interactions between the adjacent Mn(iii) ions.

Read more
A convenient one-pot synthesis of 1-aryl-substituted 4-iodopyrazol-3-ols via aromatisation and oxidative iodination reactions

Posted on 28. February, 2018.

The pyrazolones, an important class of heterocyclic compounds, are prevalent in a wide range of bioactive compounds with pharmaceutical and agricultural activities. 4-Iodopyrazole-3-ols could open the way to a quick access to many pyrazolone analogues. However, iodination is usually difficult owing to the low electrophilicity of iodide.

Read more
Synthesis and properties of D–π–A structural imidazole-triphenylamine derivatives

Posted on 27. February, 2018.

Donor–acceptor π-conjugated (D–π–A) organic molecules bearing both electron-donating and electron accepting moieties linked by a π-conjugated bridge are an important class of organic functional materials, which exhibit intramolecular charge transfer from the donor to the acceptor moiety. Numerous D–π–A structural organic molecules have been synthesised and used in solar cells, organic light emitting diodes, nonlinear optics and fluorescence sensors.

Read more
Microbial biotransformation of α-ionol

Posted on 26. February, 2018.

α-Ionol is a megastigmane derivative belonging to the most important odoriferous degradation products of β-carotene in plants and it contributes to the characteristic fragrances of many flowers.In this study, the microbial biotransformations of α-ionol by fungi were examined with the aim of producing new derivatives that could be used as potential flavour and fragrance ingredients.

Read more
Stereochemical aspects of the hydrogenolysis of derivatives of terpenoid and steroidal allylic alcohols

Posted on 23. February, 2018.

Hydrogenolysis involves the replacement of a C–X bond by a C–H bond in a reaction in which X is typically a halogen, oxygen, sulfur, selenium or nitrogen or, less commonly, carbon. In some cases it may be difficult to distinguish between hydrogenolysis and the protonolysis of an organometallic intermediate.

Read more
The ozonolysis of terpenoids, a Pandora’s box of by-products

Posted on 30. November, 2017.

The ozonolysis of alkenes is a general reaction that has made a significant contribution to the degradation and elucidation of the structures of natural products. The cleavage of alkenes by ozone has not only provided information on their immediate structural environment but also opened up the structures of compounds for further degradation. 

Read more
A three-coordinate Ag(I) complex based on the V-shaped ligand 1,3-bis(1- ethylbenzimidazol-2-yl)-2-thiapropane: synthesis, crystal structure and DNAbinding properties

Posted on 14. September, 2016.

The properties of benzimidazole and its derivatives have been studied under a broad spectrum of biological activities for many years. The benzimidazole moiety is found in various biologically active compounds having antiviral, antiulcer, antihypertensive, anticancer, and antihistaminic properties.

Read more
1 2 3 4 5 6 7 8 »