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Nanoparticles and Modulation of Immune Responses

Posted on 26. January, 2011.

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In the latest issue of Science Progress, Dr Igor Pantic of the University of Belgrade, reviews the role of nanoparticles in immune system responses. Do engineered nanoparticles have a role in producing safer and more efficient biomaterials?

Based on published data over the last 5 years, we can conclude that although much of nanoparticle-based vaccine and immunomodulation-related research today is focused on designing anti-tumour therapy strategies, nanoparticless still have great potential application as antigen carriers in vaccines against wide range of infective diseases. We can assume that further development of gene therapy and small interfering RNA targeted delivery will have great implications on both anti-tumour, and anti-infective agent vaccine development. However multidisciplinary approach, including cooperation between immunologists, geneticists, molecular biologists, as well as clinical practitioners is essential in order to resolve complex problems that await future research concerning this issue.

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